Is there any treatment for IBS

Therapy: approaches and recommendations for irritable bowel syndrome

Targeted change in the intestinal flora with antibiotics
New therapeutic strategies have set themselves the goal of not eliminating the intestinal flora of irritable bowel patients, but rather changing them in such a way that they help to improve the symptoms. The current data provides three reasons that support the use of antibiotic therapy in IBS.

  1. Antibiotics affect the composition of the intestinal bacterial flora and reduce the formation of bacterial products that can negatively affect the symptoms.
  2. Antibiotics reduce the influence of bacteria on the intestinal lining.
  3. Antibiotics change both bacteria and the host's response.


An ideal antibiotic should have a broad spectrum of activity,
i.e. act actively against gram positive and gram negative, aerobic and anaerobic bacteria, show a high bioavailability in the digestive tract without systemic effects, be safe for children, the elderly and pregnant women and still have cost-effective advantages.
Scientists have found a significant improvement in symptoms
Identify IBS patients after antibiotic therapy. In a subsequent H2 breath test, a reduced level of H2 in the breathing air was also measured. Due to the weaknesses of these studies (small number of participants, short follow-up, different endpoints) it is currently not possible to make definitive statements about the effects of antibiotic therapy.